Pain – Killer Tramadol

Tramadol is a synthetic opioid that’s proven to be a wonder drug when it comes to the management of moderate to severe pain because it controls pain without causing sedation in most cases.

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The Recommended Tramadol Dose

The usual dose of tramadol to control moderate to severe pain is one to two tramadol 50 mg (in other words, 50 to 100 mg) taken every four to six hours as needed to control pain. The total tramadol dose should never exceed 400 mg in a single 24-hour period. If you buy tramadol 180 tablets at a time, you will have enough tramadol to control your pain for slightly more than three weeks. 50 mg tramadol is the standard dose of generic tramadol. You can also purchase extended release tramadol in 100 mg tablets. The recommended dose for extended release tramadol is one 100 mg tablet once a day; if this amount is not sufficient to control pain, it can be increased to three 100 mg tablets in a day but the total dose of extended release tramadol should never exceed 300 mg in single 24-hour period. Both 50mg tramadol and 100 mg tramadol are known to lower the brain’s seizure threshold significantly; if you take more than the recommended dose, you are putting yourself at risk for seizure activity.

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Tramadol’s Mechanism of Action

Tramadol is a central nervous system depressant that acts by binding to receptors in the brain called Mu receptors that regulate the sensation of pain. Additionally, tramadol inhibits the reuptake of a neurotransmitter called serotonin that scientists believe is responsible for the feeling of wellbeing. When there are increased volumes of serotonin circulating in the bloodstream, people are less prone to become depressed. Therefore, tramadol has a significant antidepressant effect.

Side Effects of Tramadol

There are certain side effects associated with using cheap tramadol ultram to manage moderate to severe pain. While not everyone taking the medication will experience these side effects, enough do so that everyone who is using the medication should be aware of these side effects. Tramadol can cause headaches, dry mouth, vomiting, nausea, stomach cramps, constipation and/or diarrhea. These side effects are generally dose dependent: In other words, the more tramadol you take the more severe the side effects will be. However these side effects do not generally require medical intervention.

Tramadol Contraindications

As mentioned above, you should not take tramadol if you have epilepsy or any kind of history of seizures no matter what their cause. Tramadol has a significant effect on the parts of the human brain that stimulate seizures.

The Food and Drug Administration has not approved the use of tramadol in pediatric populations. If you give tramadol to anyone under the age of 18, be aware that this is an off label use of tramadol.

If you take tramadol, you should not be operating any type of heavy machinery. You should not drive a car until you see how tramadol affects you: Tramadol has significantly less sedation effect than similarly acting medications like codeine and hydrocodone; nevertheless, in some individuals it does cause significant central nervous system depression. If you are one of those individuals, you should not be taking tramadol and driving a car.

Tramadol Overdose

A tramadol overdose constitutes a medical emergency. Any individual suspected of overdosing on tramadol should be transported by ambulance to an emergency room as soon as possible. Never transport an individual suspected of tramadol overdose in a car to the hospital; medical treatment must be initiated as soon as possible.

Symptoms of tramadol overdose include extreme fatigue and drowsiness, clammy skin, pinpoint pupils, respiratory difficulties including shortness of breath, bradycardia or slow heart beat, muscle weakness, hypotension and in severe cases, coma, cardiac arrest or even death.

Emergency treatment will include the administration of activated charcoal via nasogastric tube in an effort to pump the stomach as well as the IV administration of Narcan (naloxone) which reverses tramadol’s opioid-like activity.

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