- How to choose a Tramadol Hcl 50 Mg
- What can replace Tramadol Hcl 50: protein, gainer, fat burners
- Tramadol Hcl – beneficial properties and content in foods
Tramadol and opioid withdrawal syndrome
It is known that pain in the structure of opioid withdrawal syndrome
differs in severity, and therefore requires effective therapy. Its main
Intensive pains in skeletal muscles, pains in joints,
abdominal pains of a spastic nature, less often – pains of other localization
In order to relieve pain in the Ukrainian drug practice
Various antispasmodics and analgesics are widely used. Among the last all
opioid analgesic tramadol, which is formally attributed to
means of non-narcotic series [3, 5]. However, it is known that all
opioid analgesics created to date, to a greater or lesser extent
degree, have addictive properties, i.e. the ability to cause
addiction, and tramadol is no exception to this rule.
There are numerous empirical evidence supporting this.
point of view. So, being in a hospital, patients with opiomania are not only willing
take tramadol, but actively encourage the doctor to his appointment, as tramadol hcl 50 mg: the rule
motivating the request with strong pain. Indeed, in conjunction with
benzodiazepines tramadol quickly eases the condition of patients at the height of the syndrome
cancellation. However, in most cases, patients ask, and doctors prescribe tramadol
up to 2 weeks or more, which can hardly be considered justified, even in individuals
with high daily doses of the drug and long periods of anesthesia. Such a
Doctors have no “narcological suspicion of caution” towards tramadol,
from our point of view, due to scarcity in the available literature information
about the addictive properties of this drug.
To obtain the necessary clinical information and fill this gap,
we have undertaken the present study.
The study examined the clinical picture of mental and
behavioral disorders due to non-medical use
non-narcotic opioid analgesic tramadol in 24 patients. All patients
Tramadol hcl 50 mg: was diagnosed with this drug.
All patients were male. The age of patients with tramadol addiction
was 18–35 years old. The experience of non-medical consumption of various psychotropic and
intoxicants ranged from 2 to 10 years, including the experience
use of tramadol was equal to 2-3 years. tramadol hcl 50 mg :. Fourteen patients first
intoxicant, adopted with the aim of achieving euphoria, was called
hashish, four have inhalants, two have tramadol, and two have handicraft opiates
manufacturing, one – cyclodol and even one – ephedron. All patients on
the time of the survey used tramadol without a prescription
Nine patients had a history of systematic use of opiates.
Their first intake of tramadol was due to an attempt to alleviate the condition.
cancellation, due to a break in the use of handicrafts made from
poppy straw. In the future, these patients switched to a systematic
use of tramadol tramadol hcl 50 mg:, although it allowed the occasional use of extracts from
poppy straw (about 1 time per month). In individuals addicted to artisanal opiates
manufacturing, dependence on tramadol was formed through the vicar stage
(substitution) anesthesia tramadol. The patients themselves said that
“Jumped off” (i.e., they stopped stopping narcosis of another opioid drug,
for example, heroin) using tramadol. All patients at the time of the survey
aware that they became addicted to tramadol, and the motive for seeking a doctor was
desire to stop using tramadol. Thus, there is
characteristic dynamics of the motives of the use of tramadol. First, the purpose of use
is the relief of opioid withdrawal syndrome, then a vicinal
anesthesia, finally, patients come to receive tramadol as the main
psychoactive substance causing euphoria.
All patients examined preferred tramadol capsules. Even the sick
How to choose a Tramadol Hcl 50 Mg
who practiced intravenous tramadol (sometimes in combination with
sibazon), usually used for the manufacture of injection solution
tramadol contained in capsules.
In order to achieve euphoria, patients usually consumed at one time from 2 to
10 capsules of tramadol (at 0.05). At the same time, the daily dose could reach 18-20
tramadol capsules (two observations).
The majority of interviewed patients who used tramadol, noted an increase in
mood, calm, a feeling of lightness. Some patients reported
sensation of increased activity, a surge of strength, energy.
Five patients were examined (upon admission to hospital) directly
intoxicated with 6–8 capsules of tramadol. Wherein
noted: motor and speech arousal, increased contact,
sociability, cheerfulness, talkativeness, mobility. The speech was fast, loud,
inconsistent, but coherent. However, the patients were synthns, enough
subtly caught the mood of the interlocutor, understood the jokes, reacted to them.
Strong gesticulation has taken place.
The following direct vegetative manifestations of tramadol were observed.
intoxication: facial hyperemia, lowering blood pressure on average up to 109 ± 5
mm Hg Art., slight tachycardia (up to 86 ± 8 beats per minute), decrease
reaction of pupils to light.
According to the patients, it is known that the systematic use of tramadol
accompanied by abdominal pain and constipation. Many patients, without detailing,
complained about the discomfort in the chest region, said that “it became bad with
All patients reported that occasionally with the use of tramadol
also used other intoxicants: tranquilizers, drugs
hemp, homemade opiates. Especially often to enhance
the narcotic effect of tramadol was combined with tranquilizers
Persons who use mainly tramadol, noted the growth of tolerance:
from two to three capsules of tramadol per day (at 0.05) at the beginning of anesthesia, to
twenty such capsules per day at the time of inspection.
All patients examined with the inability to use tramadol noted
mental discomfort, low mood, feeling of internal tension,
anxiety, irritability, conflict, aggressive behavior
relation to relatives. Attraction to the drug is usually worn obsessional
character (according to I. N. Pyatnitskaya, 1975) . With systematic
abuse of tramadol for a period of three to four months has formed a typical
withdrawal syndrome Its main features were vegetative manifestations:
sweating, chills, feeling of “goosebumps, running on the skin”, moderate tachycardia
(heart rate up to 90 per minute), finger tremor, total
malaise, “muscular discomfort”, inability to find a comfortable posture.
There have been sleep disorders. Duration of the period of somato-vegetative
disorders in the state of withdrawal was tramadol hcl: from 5 to 7 days. The longest
emotional disturbances persisted in the form of a feeling of internal tension,
What can replace Tramadol Hcl 50: protein, gainer, fat burners
anxiety, irritability, conflict.
The systematic use of tramadol is accompanied by characteristic
behavior changes. Some of the examined patients admitted to theft.
money from relatives and in the sale of things taken out of the house for the purpose of acquiring
tramadol, which is usually immediately used for the purpose of intoxication. In others
cases of such behavior of patients became known from the words of their
relatives who, moreover, noted negative changes in the character
the sick. According to the observations of relatives, as the dependence on
tramadol, patients became increasingly tactless, rude and prone to
lies Thus, it can be concluded that with tramadol hcl: the use of tramadol is observed
personality regression typical for all addicts is known in the literature under
the name of Broytigam syndrome (W. Brautigam) .
It should also be noted what is happening under the influence of the use of tramadol.
sharpening of premorbid psychological features characteristic of individuals
predisposed to the diseases of the narcological profile .
Patients with an established dependence on tramadol are often practiced.
episodic use of other opiates, primarily various extracts from
hand-made poppy straws. Only a small part can
to diagnose tramadol toxicomania in its pure form (only three patients
categorically denied the use of other opiates). Must be emphasized
that patients who in the past have repeatedly suffered from the withdrawal of other
opioids, comparing it with the state of abolition of tramadol, noted their
Along with common features during opioid withdrawal syndrome, when consumed
tramadol noted a number of differences. So, the speed of development and intensity
somato-vegetative manifestations of withdrawal syndrome in tramadol users,
objectively lower than in patients who used hand-made preparations
opium. In addition, in individuals who have used tramadol, in the state of its abolition
there was no diarrhea, so characteristic of opioid withdrawal syndrome. Despite
According to the estimates of the majority of members of the examined group of patients, with
dose equivalence and comparability of the anesthesia experience, the duration and
the subjective severity of the tramadol withdrawal state was greater than under the condition
cancellation of other opioids.
Studies have led to the following conclusions.
Tramadol has a significant addictive potential, which is necessary
consider when using tramadol to relieve pain in
structure of opioid withdrawal syndrome.
The resulting mental and non-medical use of tramadol
behavioral disorders are very similar to disorders caused by
other opioids (F11 disorders according to ICD-10).
The only indication for the use of tramadol in people with addiction to
opiates can be pains in muscles and / or joints that are not arrested by others
Tramadol Hcl – beneficial properties and content in foods
The time of application of tramadol tramadol hcl: in the hospital, in people with opioid addiction,
should be strictly limited to the duration of pain.
The adaptive technique of therapy providing steady
reducing doses of tramadol as the severity of pain decreases, while
the maximum dose applied should not be higher than the maximum
At least two to three days before discharge the patient from the hospital tramadol
must be canceled to ensure there are no manifestations of the cancellation state
V. Bleicher, I. Kruk. Explanatory Dictionary
psychiatric terms. – Voronezh: Modek, 1995. – p. 640.
Linsky I.V., Savkina T.V.
Psychological features as factors
predisposition to the development of mental and behavioral disorders
due to the use of psychoactive substances // Ukrainian Medical
almanac. – 2000. – Vol. 3, No. 2 (dodatok). – p. 84–85.
Young people and drugs (sociology of drug addiction)
/ Ed. V. A. Sobolev, I. P. Ruschenko. – Kharkov:
Torsing, 2000. – 432 p.
Pyatnitskaya tramadol hcl: I.N. Clinical Addiction Medicine. – L .: Medicine,
1975 – 333 p.
Shapovalov V., Shapovalova V., Kuzmіnov V.,
Khalin N., Sudikh M. Monitoring the regime for the control of tramadol and
problems of his immediate implantation we are addicted to drug addicts and toxicomans // Liki
Ukraine. – 2000. – № 11. – p. 18–19.